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Journal of Chemotherapy Volume 24, 2012 - Issue 4
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Brief Communication

First report of KPC-producing Klebsiella pneumoniae in Croatia

Branka Bedenić School of MedicineUniversity of Zagreb, Croatia; Department of Clinical and Molecular MicrobiologyClinical Hospital Center Zagreb, CroatiaCorrespondence[email protected]
,
Annarita Mazzariol Department of Pathology and DiagnosticsUniversity of Verona, Italy
,
Vanda Plečko School of MedicineUniversity of Zagreb, Croatia; Department of Clinical and Molecular MicrobiologyClinical Hospital Center Zagreb, Croatia
,
Zrinka Bošnjak Department of Clinical and Molecular MicrobiologyClinical Hospital Center Zagreb, Croatia
,
Petra Barl School of MedicineUniversity of Zagreb, Croatia
,
Jasmina Vraneš School of MedicineUniversity of Zagreb, Croatia
&
Giuseppe Cornaglia Department of Pathology and DiagnosticsUniversity of Verona, Italy
 show all
Pages 237-239 | Published online: 12 Nov 2013
 
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Abstract

In February 2011, a 78-year-old male patient was admitted to Clinical Hospital Center Zagreb with subdural haematoma. Klebsiella pneumoniae with reduced susceptibility to carbapenems was isolated. PCR revealed the presence of blaKPC, blaTEM, and blaSHV genes. Sequencing of blaKPC gene identified K. pneumoniae carbapenemase (KPC)-2 beta-lactamase. The strain belonged to ST37 clone by multilocus sequence typing. Infection control efforts limited the spread of KPC-producing clone of K. pneumoniae in our hospital so far. To our knowledge, this is the first report of a KPC-producing K. pneumoniae in Croatia.

The study was supported by Croatian Ministry of Science, Education and Sport (grant no. 108-1080-0015).

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