Abstract
Cytomegalovirus (CMV) infection in immunocompetent hosts is usually benign and does not require antiviral therapy. Rarely, however, it can be severe and life-threatening. Two immunocompetent infants with severe acquired CMV infection are reported who responded dramatically to ganciclovir with no observed side-effects. Ganciclovir should be considered in the rare instance of severe CMV infection in immunocompetent children.