Paraffin Section Molecular Biology: Review of Current Techniques

Abstract

Although molecular biology techniques for analysis of DNA and RNA have been too complex and lengthy for the routine histology laboratory, recent modifications have made them more feasible. These techniques can now be done using formalin fixed, paraffin processed tissues. Such progress could, in time, lead to improved interpretation and diagnosis of malignant disease. (The J Histotechnol 14:263, 1991)

Keywords:

• amplification
• cytogenetics
• DNA analysis
• in situ hybridization
• molecular biology
• Northern blotting
• polymerase chain reaction
• RNA analysis
• Southern blotting