Psychiatric Comorbidity in Methadone Maintained Patients

B. J. Mason PhD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

J. H. Kocsis MD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

D. Melia RN Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

E. T. Khuri MD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

J. Sweeney RN Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

A. Wells MD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

L. Borg MD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

R. B. Millman MD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

M. J. Kreek MD Laboratory of the Biology of Addictive Diseases, The Rockefeller University, P.O. Box 10025, New York, NY, USA

M. J. Kreek MD

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Abstract

Diagnosing comorbid psychiatric disorders in metha-done maintained patients may help to identify subgroups with different outcomes and needs for treatment. In this study, 75 methadone maintenance clinic patients in treatment longer than 30 days were assessed with the Addiction Severity Index, Global Assessment Scale and Mini-Mental Status Exam, and were interviewed for DSM-III-R psychiatric diagnosis using the computerized Diagnostic Interview Schedule.

Psychiatric diagnoses were prevalent in the sample with depression, phobic disorders, antisocial personality and generalized anxiety the most common. Both number of DSM-III-R diagnoses and severity of psychopathology were correlated with outcome measures such as concurrent drug abuse, family-social problems and employment status.

Overall, the results indicate that comorbid psychopathology is a significant variable in methadone maintenance patients. Clinicians working with this group should attend to these patients' needs for treatment of comorbid disorders.

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Psychiatric Comorbidity in Methadone Maintained Patients

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Psychiatric Comorbidity in Methadone Maintained Patients

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