![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
Farnesyltransferase inhibitors (FTIs) represent a promising new approach for the treatment of cancer. Although the exact mechanism of action of these compounds is not fully understood, several compounds have progressed into clinical trials with proven efficacy. This review will describe the recent patents (2000 to present) that cover FTIs in the clinic, together with other classes that are still under development.