Abstract
A novel series of 4-arylpiperidines and their salts, as well as their use in the treatment of CNS disorders, that is, depression, are disclosed. These compounds function as serotonin transporter (SERT) inhibitors and demonstrate significant activity and selectivity for SERT versus other receptors and monoamine transporters.
Keywords::
Patent Details
Title 4-Arylpiperidine derivatives and use thereof for preparing a medicament for the treatment of CNS disorders.
Assignee University of Pisa.
Inventors Nencetti, S, Lapucci A, Orlandini E, Balsamo A, Mazzoni MR.
Priority date 08/04/2005
Filing date 06/04/2006
Publication date 12/10/2006
Publication no. WO2006106432