Abstract
The patent literature pertaining to agents for the treatment of migraine headache and related disorders has been reviewed for the period of July 1, 1994 to June 30, 1995. Included are patents on serotonergic agents, i.e. 5-HT1D agonists, 5-HT2 receptor ligands and 5-HT3 antagonists as well as patents disclosing chemical entities claimed to have potential antimigraine activity via non-serotonergic mechanisms, e.g. tachykinin receptor antagonists and nitric oxide synthetase inhibitors. Relevant references from the recent scientific literature have also been cited.