The role of integrin antagonists in the treatment of inflammatory bowel disease

Abstract

Introduction: Ulcerative colitis (UC) and Crohn’s disease are chronic inflammatory diseases of the bowel associated with complex inflammatory cascades within the mucosal lining of the gut.

Areas covered: INTEGRINS and their use as therapies in UC and Crohn’s.

Expert Opinion: The anti-adhesion molecules are a welcome addition to the armamentarium of medical therapies for inflammatory bowel disease.

Keywords::

• Crohn’s disease
• immunomodulator
• inflammation
• integrin
• natalizumab
• ulcerative colitis
• vedolizumab

Notes

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