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Review

Colloidal carriers for the enhanced delivery through the skin

, , , & , PhD
Pages 737-755 | Published online: 01 Jul 2008
 

Abstract

Background: The skin is the largest organ of our body and acts as a protective barrier with sensory and immunological functions. Its peculiar structure influences the passage of bioactives and only its modulation can facilitate the drug dermal/transdermal diffusion. In the past few years research in this field has assured better use of this application area. Methods: One of the most promising approaches is the use of drug delivery devices; this review explains the state of the art of drug transport through the skin by means of vesicular (classic liposomes, Transfersomes, niosomes and ethosomes) and particulate systems. Results/conclusion: Colloidal drug delivery systems are important in the field of drug delivery systems as their different characteristics make them suitable for various purposes.

Acknowledgement

The authors are very grateful to Lynn Whitted for her revision of the language of this manuscript.

Notes

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