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Expert Review of Pharmacoeconomics & Outcomes Research Volume 7, 2007 - Issue 2
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Special Report

Alemtuzumab pretreatment and tacrolimus monotherapy in living-donor liver and kidney transplantation

Henkie P Tan Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
,
Ron Shapiro Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
,
Kusum Tom Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
,
Ngoc Thai Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
,
Wallis Marsh Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
,
Amit Basu Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
&
Amadeo Marcos Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. [email protected]
 show all
Pages 113-118 | Published online: 09 Jan 2014
 
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Abstract

We previously described the use of alemtuzumab as a pretreatment agent in 207 living-donor renal transplants, a trial that represented the largest series to date of live-donor renal and liver transplant recipients undergoing alemtuzumab pretreatment, and confirmed the short-term safety, efficacy and cost–effectiveness of this approach. This paper examines the use of the immunosuppressive combination of alemtuzumab and tacrolimus monotherapy in 47 patients with right-lobe adult living-donor liver transplantation.

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