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Expert Review of Neurotherapeutics Volume 6, 2006 - Issue 5
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Perspective

Immunization therapy in Alzheimer's disease

Felix Mor Tel-Aviv University, Weizmann Institute of Science Department of Immunology, Rehovot, Israel and Department of Medicine B, Rabin Medical Center, Affiliated to Sackler Faculty of Medicine, Israel. [email protected].
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Alon Monsonego Ben-Gurion University, National Institute of Biotechnology, and Department of Microbiology and Immunology, Faculty of Health Sciences, Beer-Sheva 84105, Israel. [email protected]
Pages 653-659 | Published online: 10 Jan 2014
 
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Abstract

Alzheimer's disease (AD) is a common and devastating neurodegenerative disease. The incidence of AD is increasing in Western societies. The current treatment of AD is mostly symptomatic and ineffective in stopping or reversing the cognitive impairment. One of the exciting and effective new treatments developed in experimental AD is immunization against amyloid-β peptide. This article provides an overview of immunization therapy in AD and examines the future prospects of this therapeutic modality.

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