62
Views
3
CrossRef citations to date
0
Altmetric
Perspectives

Can the sum of pooled data from observational studies better evaluate outcome measures for therapies in coronary artery disease?

&
Pages 155-162 | Received 22 Jun 2015, Accepted 24 Nov 2015, Published online: 27 Dec 2015
 

ABSTRACT

Randomized control trials (RCTs) are considered the gold standard in the hierarchy of evidence based medicine. Guidelines and recommendations for clinical practice are based on the strength of evidence in this hierarchical tree. This article looks at the weakness of RCTs and variance between large pooled observational data and trial results for some of the historical trials in coronary artery disease. Observational studies can supplement data from resource intensive RCTs. Guidelines for reporting and analysis however need to be rigorous. It further discusses alternate systems of hierarchies as basis for recommendations.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 99.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 611.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.