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Review

Proteomic analysis of human plasma and blood cells in nutritional studies: development of biomarkers to aid disease prevention

Pages 819-826 | Published online: 09 Jan 2014
 

Abstract

Proteomics is emerging as a valuable tool in nutritional research. Proteome analysis from plasma and blood cells can identify thousands of proteins that can potentially provide valuable new biomarkers for health, reveal early indications for disease disposition, assist in dietary responders from nonresponders, and enable the discovery of mechanisms of beneficial food component effects. This review discusses the latest developments in plasma, platelet and peripheral blood mononuclear cell proteomics, specifically in the field of nutritional proteomics, including issues relating to study design, sample preparation and data interpretation.

Financial & competing interests disclosure

The writing of this review was funded by the Scottish Government Rural and Environment Research and Analysis Directorate. The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

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