Mometasone furoate monohydrate nasal spray for the treatment of nasal congestion in allergic rhinitis

Abstract

Allergic rhinitis (AR) affects an estimated 20–40 million Americans annually. It is a multifaceted condition comprising a range of symptoms, including nasal congestion, arguably the most bothersome symptom. Of the various types of medications available for the treatment of AR, intranasal corticosteroids are considered the most effective. Mometasone furoate nasal spray is an intranasal corticosteroid with anti-inflammatory properties. It is indicated for the treatment of the nasal symptoms of seasonal AR and perennial AR in adults and children, for the prophylaxis of nasal symptoms of seasonal AR and for the treatment of nasal polyps. Numerous clinical trials have demonstrated that mometasone furoate nasal spray effectively relieves nasal congestion in adults and children with AR, while providing excellent safety and tolerability.

Keywords::

• allergic rhinitis
• intranasal corticosteroids
• mometasone furoate
• nasal congestion

Financial & competing interests disclosure

A Nayak, either through her role at the University of Illinois at Peroria or personally, has received grants, honoraria, or educational support from the following pharmaceutical companies: Abbot Immunoscience Venture; Alcon; ALK-Abello; Allergy Therapuetics; Amgen; AstraZeneca; Centocor; Curologic; Dynavax; Forest Laboratories; Genentech; GlaxoSmithKline; Integrated Therapeutics Group; Johnson & Johnson; MedImmune; MedPointe; Merck; Novartis; Pfizer; Roche; Sanofi Aventis Pharmaceuticals; Schering-Plough Research Institute; Sepracor; Teva; UCB Pharma; and Wyeth Consumer Healthcare. A Nayak has also received honoraria from the above companies for speaking at meetings sponsored by the company and for sitting on company advisory boards. The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.