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Key Paper Evaluation

Oral isotretinoin: intermittent and low-dosage regimen in acne

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Pages 267-269 | Published online: 10 Jan 2014
 

Abstract

Evaluation of: Kaymak Y, Ilter N. The effectiveness of intermittent isotretinoin treatment in mild or moderate acne. J. Eur. Acad. Dermatol. Venereol. 20, 1256–1260 (2006).

Acne is a chronic disease of the pilosebaceous follicle that affects primarily adolescents. It can be safely treated today and the physician must be aware of the main possible therapies, avoiding the treatment of discrete acne with strong systemic drugs and of severe acne with only mild local medication. Oral isotretinoin is one drug that is used successfully for some forms of acne but its optimum dose and ideal therapeutic scheme are still under discussion. Kaymak and Ilter present an intermittent and low-dose regimen, which is very interesting since it may decrease the adverse reactions, while maintaining its high efficacy.

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