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ABSTRACT
Objective: A chalazion is one of the most common presentations in ophthalmology practice and is often diagnosed and managed in busy, one-stop surgical clinics by junior doctors and allied health professionals.
Methods: Case note review of a patient with mantle cell lymphoma masquerading as chalazia.
Results: We report a case of a Caucasian 65 year-old male presenting with a 1-year history of bilateral lower eyelid swellings, diagnosed as chalazia by his general practitioner, which turned out to be mantle cell lymphoma. Mantle cell lymphoma is a type of non-Hodgkin lymphoma associated with significant morbidity and mortality. The patient was staged as IVa and responded well to chemotherapy.
Conclusion: Mantle cell lymphoma in the ocular adnexa is rare but potentially fatal and this is the first report of mantle cell lymphoma presenting as chalazia in the literature. Ophthalmologists and allied health professionals should include this in the differential diagnosis of persistent eyelid swelling and always consider biopsy of any lesion with an atypical history or unusual findings on clinical examination.
Acknowledgements
We would like to thank Dr Scott, Dr Williamson and Shanon Keen of the Hillingdon hospital for help getting pathology report and information for the paper.
Financial and competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.