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Review

Impact of uterine myomas on IVF outcome

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Pages 515-521 | Published online: 10 Jan 2014
 

Abstract

Many studies have provided evidence that uterine myomas have a significant effect on IVF outcomes and there is a large body of evidence that treatment of uterine myomas increases fertility and pregnancy rates, and decreases the rate of pregnancy loss. The evidence supports treatment of all very large myomas (>7 cm) and any cavity-deforming submucosal myomas. Thus, sonohysterography should be considered an invaluable tool in the management of IVF patients with fibroids. While subserosal myomas that are smaller than 7 cm in size and intramural myomas of less than 4–5 cm in diameter appear to have little effect on IVF outcomes, larger intramural and subserosal myomas present a clinical dilemma and more studies are needed to clarify a definitive plan for management.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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