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Review

Polycystic ovary syndrome as a developmental disorder

, , &
Pages 775-787 | Published online: 10 Jan 2014
 

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women, characterized by anovulation, hyperandrogenism and polycystic ovaries at ultrasonography. In addition to its reproductive consequences, PCOS is associated with metabolic abnormalities of which altered sensitivity to insulin appears to play a pivotal role in the development of the disorder. Currently, PCOS is considered to be a developmental disorder with varying clinical presentations depending on age. This review provides an overview of the manifestations associated with PCOS from preconception until the post-reproductive years.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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