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Review

Optimizing topical therapy for psoriasis

, &
Pages 385-402 | Published online: 10 Jan 2014
 

Abstract

There are a wide variety of topical treatment options for psoriasis. Despite their effectiveness in clinical trials, control of psoriasis in clinical practice remains a challenge. A multitude of factors limits patients’ use of medication, including frustration with poor efficacy, inconvenience, fear of side effects, financial restraints, vague application instructions, complicated regimens and unpleasant treatment characteristics. The first step to optimize topical therapy is to develop a physician–patient relationship that contributes to realistic expectations and proper use of medication. Patients should be involved in the choice of medications and vehicles. Topical corticosteroids form the foundation of treatment and topical vitamin D analogs and other noncorticosteroid agents can be used as complements to optimize long-term results.

Financial & competing interests disclosure

Kristine Busse and Ali Alikhan have no financial disclosures. Steve Feldman has received consulting, speaking and research support from Galderma, Stiefel, Astellas, Warner Chilcott, Abbott, Amgen and Centocor. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

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