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Review

Pitfalls in patch testing

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Pages 293-298 | Published online: 10 Jan 2014
 

Abstract

Allergic contact dermatitis is a common skin disease affecting both genders and individuals of any age. The patch test is the only useful in vivo method for the etiological diagnosis of allergic contact dermatitis. It is an apparently simple technique, but pitfalls may be encountered. False-positive and false-negative reactions are the most common. Times of occlusion and of reading may influence the result. Some difficulties are encountered in patients with active dermatitis or under immunosuppressive therapy, and climate conditions may interfere with the procedure. In addition, difficulties may be encountered in performing the patch test on dark-skinned patients, and patch testing in children may give some misconception due to the fact that the technique has been optimized in adults. A validated standard for readings and the interpretation of the patch test result is a recommended goal.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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