Abstract
Recent evidence has challenged the traditional paradigm in gynecology that women over the age of 45 years who are undergoing hysterectomy should also undergo prophylactic oophorectomy. Oophorectomy in young women is associated with an increased risk in cardiac disease, osteoporosis and all-cause mortality. With the increasing incidence of endometrial cancer in young women, the decision of whether to perform an oophorectomy in premenopausal women undergoing endometrial cancer staging is becoming increasingly common. We present the risks and benefits of oophorectomy, as well as discuss the literature concerning oophorectomy in young women with endometrial cancer.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.