Cost–effectiveness studies in radiation therapy

Abstract

The field of radiation therapy has made dramatic technical advances over the past 20 years. 3D conformal radiotherapy, intensity-modulated radiation therapy and proton beam therapy have all been developed in an attempt to improve the therapeutic ratio: higher cure rates with lower toxicity. Unfortunately, although the costs of radiation therapy are certainly increasing, it is unclear whether its clinical benefit has also improved. Cost–effectiveness analyses are designed to formally evaluate the cost of a treatment relative to an associated change in quality-adjusted survival. As the cost of oncologic care is increasing, it is critically important to assess the cost–effectiveness of radiation therapy. This article will describe the issues surrounding the delivery and cost of radiation therapy, and it will summarize the work that has been done to evaluate the use of cost–effectiveness in radiation oncology.

Keywords::

• cancer
• cost–effectiveness analysis
• decision analysis
• health services research
• radiation oncology
• radiation therapy
• utilities

Acknowledgements

I would like to sincerely thank Rinaa Punglia and Alec Kimmelman for their careful review of the manuscript. I also owe the reviewers a debt of gratitude for their superb suggestions on the optimal construction and focus of this article.

Financial & competing interests disclosure

The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.