Combined Diagnostic Significance of Preoperative Serum β2-Microglobulin and Routine Blood Test in Patients with High-Grade Glioma and Solitary Brain Metastasis [Erratum]

This article refers to:

Combined Diagnostic Significance of Preoperative Serum β2-Microglobulin and Routine Blood Test in Patients with High-grade Glioma and Solitary Brain Metastasis

Li L, Bu X, Wu B, et al. Cancer Manag Res. 2020;12:11735—11742.

The authors have advised that Table 1 on page 11737 and Table 2 on page 11739 are the versions uploaded during the initial submission stage instead of the final revised versions. These errors were introduced by the Editorial staff during the publication process. The correct Tables 1 and 2 are shown below.

Table 1 Clinical Characteristic of the Patients with HGG and sBM

Parameters	HGG (n=127)	sBM (n=174)	P
Age (years)	56.00 (50.00, 65.00)	63.00 (53.00, 68.00)	0.000
Gender (male/female)	67/60	102/72	0.347
β2-m (μg/L)	1771.00 (1544.00, 2063.00)	2067.00 (1649.75, 2701.00)	0.000
WBC count (×10^9/L)	6.00 (5.10, 7.50)	6.10 (5.00, 7.80)	0.905
Neutrophils (×10^9/L)	3.90 (3.10, 5.00)	4.20 (3.20, 5.70)	0.174
Lymphocytes (×10^9/L)	1.60 (1.30, 2.10)	1.40 (1.10, 1.80)	0.000
Monocytes (×10^9/L)	0.40 (0.30, 0.50)	0.40 (0.30, 0.60)	0.380
Platelets (×10^9/L)	207.00 (166.00, 237.00)	204.50 (159.00, 240.25)	0.670
RDW (%)	12.80 (12.30, 13.20)	13.00 (12.40, 13.50)	0.052
PDW (%)	16.10 (15.80, 16.40)	16.00 (15.70, 16.30)	0.305
NLR	2.38 (1.84, 3.27)	3.00 (2.20, 4.39)	0.000
MLR	0.23 (0.19, 0.30)	0.29 (0.21, 0.40)	0.000

Notes: Data were presented as median (25th, 75th percentile).

Abbreviations: HGG, high grade glioma; sBM, solitary brain metastasis; β2-m, β2-microglobulin; WBC, white blood cell; RDW, red cell distribution width; PDW, platelet distribution width; NLR, neutrophil/lymphocyte ratio; MLR, monocyte/lymphocyte ratio.

Table 2 Diagnostic Value of Preoperative Age, β2-m, NLR, MLR and Their Combinations in Patients with HGG and sBM

Markers	Formula	Cut-off	AUC	95% CI	Sensitivity (%)	Specificity (%)
Age (years)		56.50	0.625	0.561-0.689	70.70	52.85
β2-m (μg/L)		1932.50	0.655	0.594-0.717	58.05	72.36
NLR		2.45	0.634	0.571-0.698	71.26	52.85
MLR		0.28	0.622	0.559-0.686	56.32	71.54
Age+β2-m	-4.262+0.049*Age+0.01*β2-m	0.628	0.683	0.623-0.742	50.57	82.11
Age+NLR	-4.349+0.065*Age+0.212*NLR	0.541	0.683	0.622-0.744	71.26	43.90
Age+MLR	-4.291+0.064*Age+2.263*MLR	0.650	0.673	0.612-0.734	47.13	82.11
β2-m+NLR	-3.311+0.001*β2-m+0.225*NLR	0.621	0.720	0.663-0.778	55.17	86.18
β2-m+MLR	-2.926+0.001*β2-m+2.282*MLR	0.592	0.698	0.638-0.757	57.47	80.49
NLR+MLR	-0.923+1.514*MLR+0.136*NLR	0.554	0.634	0.571-0.697	59.20	67.48
Age+β2-m+NLR	-5.185+0.048*Age+0.001*β2-m+0.235*NLR	0.586	0.729	0.672-0.785	64.37	75.61
Age+β2-m+MLR	-4.894+0.049*Age+0.001*β2-m+2.145*MLR	0.569	0.716	0.658-0.773	65.52	72.36
Age+NLR+MLR	-4.470+0.064*Age+1.199*MLR+0.146*NLR	0.541	0.687	0.627-0.747	75.29	55.28
β2-m+NLR+MLR	-3.334+0.001*β2-m+0.219*NLR 0.631*MLR	0.619	0.720	0.663-0.777	56.32	84.55
Age+β2-m+NLR+MLR	-5.213+0.048*Age+0.001*β2-m+0.201*NLR+0.594*MLR	0.600	0.731	0.675-0.788	60.92	77.24

Abbreviations: HGG, high grade glioma; sBM, solitary brain metastasis; β2-m, β2-microglobulin; NLR, neutrophil/lymphocyte ratio; MLR, monocyte/lymphocyte ratio; AUC, area under the curve.