Dear Editor
In the last decade, the treatment and prognosis of chronic obstructive pulmonary disease (COPD) patients have been improved by noninvasive ventilation (NIV).Citation1
However, the choice between invasive mechanical ventilation (IMV) and NIV, is still influenced by several critical factors.Citation2 We read with interest the original article and related commentary by Scarpazza et al, reporting a very high NIV success rate in patients with acute hypercapnic respiratory failure due to acute exacerbations of COPD (AECOPD) with related reduction in IMV-associated complications.Citation3 Nevertheless, although NIV represents one of the most important progresses in pulmonary medicine in the last decade, we believe that there are still some unresolved questions.
First, there are interhospital differences in the organization of NIV provisions.Citation4 Second, the final decision on indications and modalities of NIV in patients with AECOPD should rely on experience and guidelines.Citation5 Third, there is a subgroup of patients not yet clearly evaluated, such as elderly with comorbidities, where studies are limited and do not provide a clear message. Furthermore the influence of COPD stage and underlying cause of AECOPD in outcome of mechanical ventilation is difficult to estimate.Citation6 Fourth, devices and settings differ among countries, sometimes with scarce perspectives of improvement due to economic aspects.Citation7
We believe that there is clear scientific evidence of effect of NIV in these patients. The room for IMV is small, but it must still have open windows to any situation in deciding the type of mechanical ventilation.
Disclosure
The authors report no conflicts of interest in this correspondence.
Dear Editor
We completely agree with Esquinas Rodriguez, Scala and Ambrosino. In fact, the terms used in the title of our article were “shrinking the room” and not “abandoning” invasive mechanical ventilation (IMV). Concerning the issues raised by the authors, we are of the same opinion about the interhospital differences and the need for experience in deciding the appropriate ventilation for patients. In our hospital, noninvasive ventilation (NIV) is started directly in the emergency department following evaluation in most cases by both the resuscitator and a pulmonologist, and continued in semi-intensive respiratory therapy, with a pulmonologist available 24 hours a day. NIV has been used by our group from approximately 20 years ago, each pulmonologist in our unit has the expertise to decide if it is appropriate for a patient with severe acute respiratory failure. For elderly patients, the lack of clear indications was the main basis for the studies we performed on such a subgroup,Citation1,Citation2 which was also investigated by other authors who introduced the concept of rescue NIV, where the NIV is the only feasible therapeutic option.Citation3 It is clear that the economic issue influences the availability of devices and settings, but we believe it is necessary from the legislative point of view, at least in Italy, that within the emergency and urgency departments of a medium-size hospital, a semi-intensive respiratory care unit is accessible.
In addition to the significant benefits for some patients by saving an intensive care unit admission or a tracheotomy because of difficult weaning, and therefore recovering substantial economic resources in the subgroup of elderly patients with comorbidities, NIV represents the only therapeutic option possible.
Ultimately, the conclusion by Esquinas Rodriguez et al that “The room for IMV is small, but it must still have open windows” is also our view.
Disclosure
The authors report no conflicts of interest in this correspondence.
References
- ScarpazzaPIncorvaiaCdi FrancoGEffect of noninvasive mechanical ventilation in elderly patients with hypercapnic acute-on-chronic respiratory failure and a do-not-intubate orderInt J Chron Obstruct Pulmon Dis2008379780119281095
- ScarpazzaPIncorvaiaCAmboniPLong-term survival in elderly patients with a do-not-intubate order treated with noninvasive mechanical ventilationInt J Chron Obstruct Pulmon Dis2011625325721814461
- NavaSGrassiMFanfullaRNon-invasive ventilation in elderly patients with acute hypercapnic respiratory failure: a randomised controlled trialAge Ageing20114044445021345841