A Response to Article “Distribution of Mcr-1 Harboring Hypervirulent Klebsiella pneumoniae in Clinical Specimens and Lytic Activity of Bacteriophage KpnM Against Isolates” [Response to Letter]

This article responds to:

A Response to Article “Distribution of Mcr-1 Harboring Hypervirulent Klebsiella Pneumoniae in Clinical Specimens and Lytic Activity of Bacteriophage KpnM Against Isolates” [Letter]

Dear editor

We acknowledge the effort made by the author to craft the response to our recent publication in infection and drug resistance.¹ We are pleased that the author appreciated our work and found the results of the study promising to fight antibiotic resistance and resistant superbugs like Klebsiella pneumoniae. In addition to that, the author raised some fair queries regarding the methods and suggested possible explications. For instance, though we have characterized the isolates in the present investigation, we mentioned only the string test as a phenotypic test to characterize the hypervirulent isolates, which served the purpose of the study.² However, as the authors suggested that mentioning the detailed molecular identification of the hypervirulent strains could be a better procedure. Taking it together, we appreciate the author for valuable suggestions and future directions to decipher the molecular mechanisms involved in the lytic activity of bacteriophage KpnM, which we shall consider in our imminent research plans.³

Disclosure

All the authors reported that there is no conflict of interest in this communication.