Assessment of Post-COVID-19 Quality of Life Using the Quality of Life Index

Abstract

Background

COVID-19 has impacted many aspects of peoples’ quality of life (QOL).

Aim

To assess the QOL of post-COVID-19 cases and determine their associated sociodemographic attributes.

Methods

A cross-sectional community-based study targeted recovered COVID-19 cases using an online questionnaire. An Arabic version of the Quality of Life Index (QLI) was evaluated for reliability and validity using Cronbach’s alpha and Spearman’s product moment tests, respectively. Descriptive analysis, Mann–Whitney U, Kruskal–Wallis H, and Spearman correlation tests were used to investigate the relationships between QOL and study independent variables, including sociodemographic characteristics, time since infection, intention for vaccination, perception of the influence of COVID-19 on general health, history of hospitalization, and history of chronic illness. Subgroups were compared using a Student’s t-test for normally distributed data and the Wilcoxon rank-sum test or the Kruskal–Wallis test for non-normally distributed data.

Results

In a sample of 449 respondents, the total QLI score was 22.64 ± 4.36; for subscales, it ranged from 20.86 ± 5.04 to 24.99 ± 4.74. Males had significantly higher health and functioning subscale (HFSUB) scores compared to females (p = 0.033). Employed cases had significantly higher social and economic subscale (SOCSUB) scores than unemployed cases (p = 0.000). Married people reported significantly higher family subscale (FAMSUB) scores (p = 0.000) than unmarried people. People who believe that their general health was affected by COVID-19 had significantly lower HFSUB and psychological and spiritual subscale (PSPSUB) scores (p = 0.000 and p = 0.021, respectively). Individuals with a history of hospital admissions scored lower on PSPSUB (p = 0.000). Age was significantly associated with both SOCSUB (p = 0.006) and FAMSUB (p = 0.040).

Conclusion

Sociodemographic attributes of people with a history of COVID-19 revealed significant differences in some QOL domains, as measured by the Arabic version of the generic QLI. History of hospitalization and beliefs about COVID-19’s impact on general health negatively influenced individual’s HFSUB and PSPSUB.

Keywords:

• quality of life
• COVID-19
• post-COVID-19 cases
• Saudi Arabia
• quality of life index

Introduction

In late 2019, a novel coronavirus started spreading from Wuhan, China, to the entire globe.¹ The World Health Organization officially named the disease caused by this virus Coronavirus Disease 2019 (COVID-19).² Currently, the world is still struggling with the spread of COVID-19. The numbers of cases and deaths are increasing every day (available at https://covid19.who.int/). The virus has increased the burden on health professionals and health care systems in many countries.^3–6 In Saudi Arabia, the first case of COVID-19 was confirmed in March 2020. The number of cases continued to rise until a significant decrease occurred at the end of 2020, but then, an increase began again in April 2021 (data available at https://covid19.moh.gov.sa/). However, the total number of COVID-19 cases in Saudi Arabia has remained relatively low due to prompt precautionary action taken by the government.⁷ As a lockdown started at the end of March 2020, it was predicted that confirmed cases would be reduced by 400,000 by the end of September 2020.⁸ Ultimately, the number of cases was successfully decreased due to the lockdown and precautionary measures implemented during the mentioned period.

Exploration into the impact of the COVID-19 pandemic on the quality of life (QOL) for the general populations of Saudi Arabia, Lebanon, Italy, the United Kingdom, the United States, Morocco, and China has shown substantial influences, especially regarding physical, psychological, social, and spiritual health.^9–18 The QOL of health care professionals was also impacted by COVID-19.^19,20 Many studies have reported that various symptoms are experienced during and after COVID-19 infection.^21–24 Other studies have shown that post-COVID-19 symptoms are minimal for about 1–6 months after diagnosis, except for people with comorbidities.^25,26 During the pandemic, families have encountered many issues that have influenced their well-being, such as violence, conflict, and divorce.^27,28 Economists have also witnessed deterioration as a consequence of the lockdowns and quarantines.^29,30 COVID-19 patients have experienced mental health issues, such as depression.⁹ Additionally, poor QOL has been reported after one month for discharged COVID-19 patients, especially concerning physical and psychological aspects of well-being.^31,32 After three months, their QOL has been reported to still be significantly lower than the normal population.³³ Moreover, in terms of care, non-hospitalized COVID-19 patients have been reported to either be self-dependent (independent) or care-dependent (depend on others).^34,35 QOL has been explored for non-hospitalized patients, showing no difference from the normal population. However, no large impact was found in the mental health domain.³⁶

QOL is defined as an individual’s feelings of well-being in terms of satisfaction with important aspects of life.³⁷ Individual preferences in defining their goals, choices, and expectations in life will help determine their QOL.³⁸ Many studies have explored the QOL of recovered COVID-19 cases in the general population, hospitalized patients, and patients with chronic illness.^14,31,33,39 Additionally, recent studies have explored the QOL of those who have recovered from COVID-19 at home without medical intervention.³⁶ Therefore, we aim to assess the QOL for recovered COVID-19 cases in Saudi Arabia, including non-hospitalized, hospitalized, and chronically ill patients, to understand the impact of COVID-19 on their QOL and its subscales and answer the following study objectives: identify the sociodemographic profile of recovered COVID-19 cases; assess the mean score of the overall Quality of Life Index (QLI) and its subscales among recovered COVID-19 cases; and measure significant differences of sample sociodemographic profiles, time of infection, intention for vaccination, and perception of the influence of COVID-19 on general health, history of hospitalization, and history of chronic illness in relation to QOL and its subscales. As individuals respond differently to COVID-19, the expected outcome of this study was to find a significant decline in all or some aspects of QOL based on people’s sociodemographic characteristics and the impact of other factors, such as time since infection, intention for vaccination, and the perception of the influence of COVID-19 on general health, hospitalization, and chronic illness.

Materials and Methods

Design

An explorative, cross-sectional, community-based study design used a self-reported electronic questionnaire, which was distributed online among survivors of COVID-19 in the Kingdom of Saudi Arabia.

Sample

Recovered COVID-19 cases were targeted according to the following inclusion criteria: those who were aged 18 or older and those with a confirmed history of COVID-19 infection. The exclusion criteria were those who were not officially confirmed to have been infected with COVID-19. By the end of data collection (late May 2021), the Saudi Ministry of Health announced a cumulative 443,460 total cases and 426,589 total recoveries (data available at https://covid19.moh.gov.sa/). Based on the total number of 426,589 recovered cases, and assuming a 95% confidence interval with a 0.5 margin of error, the calculated sample size was expected to reach 384 responses or more.

Data Collection

Using social media (eg, WhatsApp, Twitter, and text messages), data were collected between March and May 2021 using the convenient snowball sampling technique (ie, participants were asked to refer the questionnaire link to individuals with a known history of COVID-19 infection).

Instrument

A three-part questionnaire was used. Part 1 consisted of questions about the demographic characteristics of the subjects, including their age, sex, marital status, level of education, employment status, time since diagnosis, symptoms experienced, interest in vaccination, and perception of the influence of COVID-19 on general health. Part 2 included questions about the subjects’ history of chronic illness and hospitalization due to COVID-19. Part 3 was the generic version of the QLI, an instrument developed to measure individuals’ QOL.⁴⁰ The score includes the sum of patients’ satisfaction and importance of QOL domain scores.⁴¹ The QLI was tested for psychometric properties, and it has the following four major subscales: health and functioning (HFSUB), social and economic (SOCSUB), psychological and spiritual (PSPSUB), and family (FAMSUB).^37,42 The Arabic version of the generic 66-item QLI questionnaire measured questions on a 6-point Likert-type scale (ie, very dissatisfied to very satisfied and very unimportant to very important). It comprised the following four subscales: HFSUB, SOCSUB, PSPSUB, and FAMSUB. The scores ranged from 0 to 30, with higher scores indicating better QOL. The instrument was tested among the Arab population with evidence of internal consistency.⁴³ The QLI developer and the author of the Arabic translation were contacted, and approvals were obtained from both. Among people with a history of COVID-19, the study questionnaire was checked for reliability using the Cronbach’s alpha test, which revealed an alpha value of 0.94, indicating acceptable evidence of internal consistency.⁴⁴ The construct validity was checked by the Spearman’s product moment test (Appendix A- Table S1).⁴⁵ All questions measuring QOL were reliable and valid. Reliability estimates for the instrument used in this study were comparable with Halabi’s findings of 0.94 and 0.97; all were above 0.80, indicating an adequate level of internal consistency.^43,44 The Cronbach’s alphas of all subscales were more than 0.80, except for SOCSUB at 0.77 and FAMSUB at 0.74, which is acceptable under Nunnally and Bernstein’s criterion for adequate internal consistency.⁴⁶ Using the current sample, the QLI test for validity showed that all 33 items forming the four subscales were correlated, which indicates appropriate construct validity for determining the extent of the relationship between the measures that determine theoretical constructs.^44,45

Analysis

Descriptive statistics for the demographic information were computed for each of the following variables: demographic characteristics; related COVID-19 questions; the HFSUB, SOCSUB, PSPSUB, and FAMSUB subscales; and the total QLI level. The categorical variables were presented as frequencies and percentages and as continuous variables as mean ± standard deviation (SD). The subscale and QLI scores were checked for normality using the Shapiro–Wilk test, which showed a non-normal distribution. The QOL subscales and QLI scores were calculated according to the instructions of Ferrans and Powers (available at https://qli.org.uic.edu/). The means of the QOL subscales and the QLI total were compared between different sociodemographic characteristics and COVID-19-related questions using the Mann–Whitney U-test and the Kruskal–Wallis H-test. To compare the QLI and subscores of patients with respect to time since diagnosis of COVID-19, participants were divided into three groups (0–3 months, 3–6 months, and more than 6 months). The findings were presented either as the mean ± SD or as a percentage of the entire group from which the categorical data were summed. The Student’s t-test was used for normally distributed data, and the Wilcoxon rank-sum test or the Kruskal–Wallis test was performed for non-normally distributed data in the quantity distributions between patient subgroups (Appendix B- Tables S2 and S3). Statistical significance was denoted by p-value < 0.05. All statistical analyses were carried out using SPSS software.

Ethical Consideration

This study was conducted in accordance with the Declaration of Helsinki. Ethical approval was obtained from the Institutional Review Board of the General Directorate of Health Affairs, Tabuk Region (Registration No. H-07- TU-077) and protocol #TU-077/021/079. Participants received a full description of the purpose of the study and were informed about the researchers’ commitment to research ethics. Moreover, no personal identifier was required, and only the principal investigator can access the data. In addition, participants were informed that data will be used and published only for research purposes. Informed consent was attached at the beginning of the online survey. Individuals who agreed to participate proceeded to the questionnaire.

Results

The study included a total of 449 post-COVID-19 cases. The mean age of participants was 36.06 ± 11.34 years, and the average number of days that had passed since diagnosis was 194. Most of the sample cases were female (73.9%) and had a graduate level of education (88.2%). Half of the cases were employed (53.5%) and more than half were married (64.6%). COVID-19 produced symptoms in 403 (89.8%) of the cases. Two-thirds of the sample (66.1%) were interested in vaccination against COVID-19. Nearly half responded that COVID-19 did not affect their general health. The majority of the sample had not been hospitalized (91.3%) and did not have a history of chronic illness (83.5%) (Table 1).

Table 1 Socio-Demographic Characteristics of All Cases and Responses to Covid-19 Related Questions (n = 449)

Characteristics	N (%)
Age in years (Mean ± SD)	36.06 ± 11.34
Time since diagnosis (days)	194.37 ± 86.64
Gender
Male	117 (26.1)
Female	332 (73.9)
Education level
Primary	1 (0.2)
Intermediate	4 (0.9)
High school	52 (12)
Diploma	8 (1.8)
Graduate	368 (82.0)
Master’s Degree	11 (2.4)
Doctoral degree	2 (0.4)
Employment status
Student	77 (17.1)
Employed	240 (53.5)
Not employed	132 (29.4)
Marital status
Single	140 (31.2)
Married	290 (64.5)
Divorced	13 (2.9)
Widowed	6 (1.3)
Symptoms of COVID-19
Yes	403 (89.8)
No	46 (10.2)
Interested in vaccination against COVID-19
Yes	297 (66.1)
No	152 (33.9)
Effect of COVID-19 on general health
Yes	124 (27.6)
Maybe	127 (28.3)
No	198 (44.1)
History of hospitalization
Yes	39 (8.7)
No	410 (91.3)
History of chronic illness
Yes	74 (16.5)
No	375(83.5)

Abbreviation: SD, standard deviation.

The mean QLI subscale scores were as follows: HFSUB (21.86 ± 5.03), SOCSUB (20.86 ± 5.04), PSPSUB (24.99 ± 4.74), and FAMSUB (24.20 ± 4.87). The mean total QLI score was 22.64 ± 4.36 (Table 2).

Table 2 The Mean Subscales and Total Quality of Life Scores (n = 449)

Scales	Mean	SD
Health and functioning subscale score	21.86	5.03
Social and economic subscale score	20.86	5.04
Psychological/spiritual subscale score	24.99	4.74
Family subscale score	24.20	4.87
Total score (QLI)	22.64	4.36

Abbreviations: SD, standard deviation; OLI, Quality of Life Index.

When assessing the correlation between age, time since diagnosis, and QLI subscales, we found there was no significant correlation between age and the subscales, except for with FAMSUB (p = 0.04); time since diagnosis and subscales and total QLI score was observed (p > 0.050). However, the subscales were significantly positively correlated with each other and with the total QLI score (all p-values = 0.000) (Table 3).

Table 3 Correlation Between Age, Time Elapsed from Diagnosis, Subscale Scores and Total Quality of Life Index (n=449)

	Age	Time Elapsed from Diagnosis	HFSUB Score	SOCSUB Score	PSPSUB Score	FAMSUB Score	Total QLI Score
Age	1.000	0.066	−0.025	0.130*	0.079	0.097	0.059
Time elapsed from diagnosis		1.000	0.021	0.019	0.028	0.019	0.025
HFSUB score			1.000	0.692**	0.772**	0.707**	0.945**
SOCSUB score				1.000	0.700**	0.534**	0.845**
PSPSUB score					1.000	0.613**	0.880**
FAMSUB score						1.000	0.780**

Notes: test used=Spearman correlation coefficient (r). *P < 0.05, **P < 0.00.

Abbreviations: HFSUB, health and functioning subscale; SOCSUB, social and economic subscale; PSPSUB, psychological and spiritual subscale; FAMSUB, family subscale; OLI, Quality of Life Index.

By examining the relationship between sample sociodemographic characteristics and QOL subscales, we found that males (22.74 ± 5.33) had significantly higher HFSUB scores than females 21.59 ± 4.90 (p = 0.033). Employed cases (21.55 ± 5.33) had significantly higher SOCSUB scores than unemployed cases (19.59 ± 5.14; p = 0.000). The QLI total was similar for all cases across sociodemographic characteristics. Those whose general health was affected by COVID-19 had significantly lower HFSUB scores (p = 0.000) and PSPSUB scores (p = 0.021). A comparison of QOL subscales for individuals with a history of chronic infections against those who had no chronic infection showed that SOCSUB and PSPSUB scores were higher for the former (Table 4). However, individuals with a history of hospital admissions had lower SOCSUB and PSPSUB scores than individuals who had not (Table 4).

Table 4 Mean Difference Between QOL Scales and Socio-Demographic Characteristics and COVID-19 Related Questions (n = 449)

Characteristics	HFSUB Mean±SD	Mann–Whitney U	SOCSUB Mean±SD	Mann–Whitney U	PSPSUB Mean±SD	Mann–Whitney U	FAMSUB Mean±SD	Mann–Whitney U	QLI Mean±SD	Mann–Whitney U
Gender		16,760.500*		18,663.000		19,688.000		17,529.000		18,349.000
Male	22.74 ± 5.33		20.70 ± 4.69		24.95 ± 4.85		24.79 ± 4.95		23.02 ± 4.49
Female	21.59 ± 4.90		20.97 ± 5.18		25.05 ± 4.70		24.03 ± 4.82		22.54 ± 4.33
Education level		9680.000		9375.500		9868.500		9284.000		9896.500
Below Graduate	22.53 ± 4.56		20.36 ± 4.97		24.60 ± 5.28		24.60 ± 4.58		22.76 ± 4.18
Graduate or higher	22.10 ± 4.91		20.89 ± 5.23		25.11 ± 4.61		24.28 ± 4.96		22.78 ± 4.34
Employment		14,813.000		12,432.500**		15,199.500		15,781.000		14,305.000
Employed	21.85 ± 5.03		21.56 ± 4.79		25.06 ± 4.67		24.32 ± 4.69		22.83 ± 4.32
Not employed	21.32 ± 4.79		19.59 ± 5.14		24.67 ± 4.87		24.27 ± 4.83		22.06 ± 4.26
Marital status		20,193.000		18,021.500*		19,813.500		15,734.500**		198,990.000
Single	21.76 ± 5.66		21.17 ± 5.62		24.52 ± 5.34		22.63 ± 5.75		22.09 ± 5.09
Married	21.87 ± 4.79		21.21± 4.80		25.15 ± 4.48		25.04 ± 4.17		22.89 ± 4.04
Symptoms		7832.500		7833.500		8709.500		7925.000		8213.000
No	22.77 ±4.68		20.68 ± 4.50		24.83± 4.09		23.40 ± 4.20		22.01 ± 3.95
Yes	22.02 ±5.07		20.93 ± 5.12		25.05± 4.81		24.32 ± 4.93		22.75 ± 4.42
Interested in vaccination		20,572.000		22,634.500		21,750.500		20,602.000		21,083.500
No	22.35 ±5.39		21.01 ± 4.62		25.30 ±4.68		24.68 ±4.95		23.01 ±4.39
Yes	21.65 ± 4.84		20.84 ± 5.67		24.89 ±4.77		24.00 ±4.81		22.50 ±4.36
Effect on health		11,010.500**		11,864.000		11,864.000*		12,488.500		11,635.000
No	22.76 ±5.18		21.28 ±5.02		25.36±4.74		24.38 ±5.01		23.20 ±4.50
Yes	20.39 ±5.16		20.47 ±4.88		24.14±4.88		23.84±4.82		21.73 ±4.32
History of hospitalization		7299.500		7604.000		7555.000**		7800.500		7473.000
No	27.65 ±3.31		27.31 ±3.8		30.00 ±0.00		27.7 ±3.25		28.07 ±2.72
Yes	21.86 ±5.04		20.87 ±5.04		25.00 ±4.74		24.2±4.87		22.65 ±4.37
Chronic disease		12,832.000		13,068.000		13,014.500		13,909.000		13,773.500
No	22.06 ±4.87		20.80 ±5.16		24.97 ±4.72		24.23 ±4.90		22.70 ±4.33
Yes	21.04 ±5.79		21.40 ± 4.47		25.33 ±4.84		24.25± 4.72		22.52 ±4.73

Notes: Test used= Mann–Whitney U-test. * P < 0.05, ** P < 0.001.

Abbreviations: HFSUB, health and functioning subscale; SOCSUB, social and economic subscale; PSPSUB, psychological and spiritual subscale; FAMSUB, family subscale; OLI, Quality of Life Index.

In comparison of mean QLI and other subscales with respect to time since diagnosis of COVID-19, the SOCSUB scores gradually increased in patients who had been diagnosed with COVID-19 0–3 months before (19.80 ± 5.21), 3–6 months (21.08 ± 5.21), and more than 6 months (21.11 ± 4.87). Similarly, FAMSUB scores were lower in patients at 0–3 months (23.90 ± 5.13) than in patients who had been diagnosed 3–6 months before (24.55 ± 4.74) and more than 6 months (24.11 ± 4.88). Figure 1 represents the clustered bar mean of QLI and other subscales with respect to time in months after COVID-19 diagnosis.

Figure 1 Clustered bar mean of QLI and other subscales with respect to time in months after COVID-19 diagnosis.

Abbreviations: HFSUBa, health and functioning subscale; SOCSUBb, social and economic subscale; PSPSUBc, psychological and spiritual subscale; FAMSUBd, family subscale; OLI, Quality of Life Index.

A comparison of the QOL subscales for individuals with a history of chronic infections and those with no chronic infections showed no significant difference (Table 4). Figure 2 represents the clustered bar mean of QLI and other subscales for patients with and without chronic illness. Similarly, patients who had been admitted to the hospital for COVID-19 reported lower PSPSUB scores (25.00 ± 4.74) than those who had not (30.00 ± 0.00). The remaining subscale scores and QLI were more or less similar in patients with or without hospital admissions. Figure 3 represents the clustered bar mean of QLI and other subscales for patients with and without hospital admissions.

Figure 2 Clustered bar mean of QLI and other subscales according to history of chronic illness.

Abbreviations: HFSUBa, health and functioning subscale; SOCSUBb, social and economic subscale; PSPSUBc, psychological and spiritual subscale; FAMSUBd, family subscale; OLI, Quality of Life Index.

Figure 3 Clustered bar mean of QLI and other subscales according to history of hospital admission.

Abbreviations: HFSUBa, health and functioning subscale; SOCSUBb, social and economic subscale; PSPSUBc, psychological and spiritual subscale; FAMSUBd, family subscale; OLI, Quality of Life Index.

Discussion

This study assessed the QOL of people who have recovered from COVID-19 using the QLI and exploring significant correlations with sample sociodemographic characteristics. As the instrument was valid, it was expected to demonstrate a strong association between the total QLI score and its subscales and between the subscales. These associations were consistent with other QOL studies, although a different tool was used.¹⁴ In the current study, the SOCSUB mean score was the least comparable to the other subscales. Indeed, COVID-19 patients faced quarantine for 10–14 days with zero social interaction, so the prevalence of loneliness was high among those who experienced COVID-19-related symptoms.⁴⁷ Despite the benefits of social distancing and quarantine, there were consequences on individuals’ social well-being.^8,48 Therefore, Saudi Arabia faces economic and social challenges as a consequence of government measures to reduce the spread of COVID-19 infection.⁴⁹

When examining the relationship between the total QLI score and its subscales with the sample sociodemographic attributes, age showed a significant correlation with FAMSUB. This association can be explained by familial bonding and support in Saudi culture, especially for sick people.⁵⁰ Both young and older adults were at risk of loneliness and its consequences for their well-being.^51,52 Lower levels of general health, physical function, and spiritual well-being were also associated with older age.^33,53 The time since diagnosis had no correlation with the QLI score or its subscales. This finding was similar to that of Garratt et al, who found that QOL has overall good scores except for mental well-being.³⁶

Gender was associated with HFSUB, as males reported higher scores than females, which contradicts other studies reporting that males face more deterioration and complications than females.⁵⁴ The sample had a majority of female participants; however, males have been found to be more susceptible to COVID-19 infection.⁵⁵ Many studies have shown that males also have higher levels of disease severity and fatality than females.^54,56 Employment status had a significant relationship with SOCSUB. Indeed, there has been a massive effect of COVID-19 on the global economy that has influenced individuals’ socioeconomic position.³⁰ Many people have lost their jobs during the pandemic, leading to a reduction in economic activities.⁵⁷ Therefore, the influence of COVID-19 on employment has been universal, not only in Saudi Arabia. Married participants reported higher FAMSUB scores than single participants. Although many studies have shown that COVID-19 may have negative influences on couples’ relationships,^58,59 Saudi culture is characterized by strong relationships among families, especially those with a sick spouse.⁵⁰

Participants’ perceptions of the impact of COVID-19 on their health had significant associations with HFSUB and PSPSUB. This means that participants could interpret their own perceptions of their QOL; one-half mentioned that it had or might have an effect on their health. Many studies have supported this by reporting that COVID-19 patients have experienced a decline in physical, psychological, and spiritual health.^9,16,25,31

When comparing groups, SOCSUB and FAMSUB scores gradually increased with time. However, based on previous studies, COVID-19 patients cannot return to their normal lives within 1–6 months of hospital discharge, especially those with chronic illness.^25,26,33 Our findings showed that PSPSUB was lower among those who had been hospitalized. One study reported that the prevalence of depression was associated with hospitalized patients.⁹ In addition, psychological impairment was found one month after hospital discharge.³¹ Symptoms experienced, participants’ interest in vaccination, and chronic illness had no significant association with the total QLI score or any of its subscales. Overall QOL among the studied sample was 22.6 compared with the maximum score of the instrument of 30. Other studies have shown a greater decline in QOL after COVID-19 infection, especially in the physical and psychological well-being of hospitalized patients.^9,31,33 In contrast, one contradicting study reported a good QOL of non-hospitalized COVID-19 patients.³⁶

This study has some limitations. The concept of QOL is still being questioned, largely because it is based on peoples’ preferences. While perspectives of QOL may differ on an individual basis, the measures and instrument-scoring requirements in this study constrained peoples’ choices.³⁸ The results cannot be generalized for the following reasons. The sample size might not be representative, and the online questionnaire was self-reported. Response bias could be expected (ie, when participants answer to please the researcher). Furthermore, the cross-sectional nature of the study and time limitations in data collection (ie, two months) could not account for the long-term effects of COVID-19 on patients’ QOL. The lack of a baseline measure did not allow for comparing QOL after COVID-19 infection. The variation of time since diagnosis could be a confounder. The assessment of mental health was not applicable for this study, as mental well-being was not part of the QLI.

Many areas of COVID-19-related issues have not yet been explored. This invites researchers to explore more-detailed QOL findings in relation to COVID-19, especially for non-hospitalized patients, who account for the majority of infected cases. Follow-up studies with a wide range of sample characteristics are recommended to allow for comparison. Further physical and psychological evaluations would be beneficial for both hospitalized and non-hospitalized patients who have contracted COVID-19 infection in order to plan future interventions to help them recover from the pandemic.

Conclusion

For use in people with a history of COVID-19, the Arabic version of generic QLI was valid and reliable. COVID-19 has altered many aspects of people’s QOL. Sociodemographic characteristics of individuals with a history of COVID-19 revealed significant differences in some domains of QOL, as measured by the Arabic version of the generic QLI. People’s beliefs about the impact of COVID-19 on general health and history of hospitalization were mainly influenced by their health, functioning, psychological, and spiritual well-being.

Disclosure

The author declares no conflicts of interest in this work.