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Priority Paper Evaluation

Association of Suicide in the Elderly and SSRI Antidepressants: Information from a Population-Based Study

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Pages 917-918 | Published online: 14 Dec 2006
 

Abstract

Evaluation of: Juurlink DN, Mamdani MM, Kopp A, Redelmeier DA: The risk of suicide with selective serotonin reuptake inhibitors in the elderly. Am. J. Psychiatry 163, 813–821 (2006). A population-based study of 1138 completed suicide cases matched to 4552 comparison cases found a fivefold higher risk of completed suicide in the first month of treatment with selective serotonin reuptake inhibitors relative to other antidepressants; however, the absolute risk of suicide was low. There was no difference between antidepressants regarding suicide risk after the first month of treatment. Men, more than women, were found to complete suicide.

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