Abstract
Anaphylaxis is a potentially fatal generalized hypersensitivity reaction leading to multiorgan dysfunction. It involves multiple mediators using several different pathways for the development of a systemic response. The elderly differ from other age groups in terms of the risk factors, causative agents and the development of compensatory mechanisms. The presence of comorbidities and polypharmacy has a marked influence on treatment and outcome in the elderly. This article aims at a general understanding of anaphylaxis with special reference to the elderly.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.