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Review

Predictive Relevance of ncRNAs in Non-Small-Cell Lung Cancer Patients with Radiotherapy: A Review of the Published Data

Pages 1149-1159 | Received 05 Jan 2018, Accepted 14 Jun 2018, Published online: 07 Sep 2018
 

Abstract

Radiotherapy is one of the most commonly used methods to treat non-small-cell lung cancer. However, radiotherapy, especially thoracic radiotherapy, is always accompanied by radiation-induced complications or radioresistance. In this regard, ncRNAs, including miRNAs and lncRNAs, have received considerable interest for their predictive relevance. This review article illustrates the recent findings about the possible involvement of ncRNAs, mainly miRNAs and lncRNAs, in radioresistance and radiation-induced complications and their potential use for predicting radiation-induced complications and radiotherapy response.

Acknowledgements

The author thanks all anonymous reviewers for their comments and constructive criticism.

Financial & competing interests disclosure

The author Q Huang discloses no financial interests and is funded through the Natural Science Foundation of Fujian Province, PR China (grant no. 2016J01579) and the Natural Science Foundation of Fujian Province, PR China (grant no. 2017J01329). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Additional information

Funding

The author Q Huang discloses no financial interests and is funded through the Natural Science Foundation of Fujian Province, PR China (grant no. 2016J01579) and the Natural Science Foundation of Fujian Province, PR China (grant no. 2017J01329). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

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