Comparison of the effect of Uric Acid/Albumin Ratio on Coronary Slow Flow with Other Inflammation-Based Markers

Abstract

Background:

Many inflammation-based markers (IBMs) have been shown to be closely related to coronary slow flow (CSF), but the effect of the uric acid/albumin ratio (UAR) on CSF and its relationship with other IBMs are not clearly known. In this study, we aimed to compare the effects of UAR and other IBMs on CSF.

Methods:

After the exclusion criteria, 126 patients with CSF detected on coronary angiography and 126 subjects with normal coronary flow as the control group were included in the study.

Results:

UAR was determined as an independent predictor for CSF. In addition, the UAR was superior to other IBMs in detecting CSF (p < 0.05 for all).

Conclusion:

This study is the first to investigate the effect of UAR on CSF in comparison with other IBMs.

Keywords::

• coronary slow flow
• inflammation-based markers
• uric acid/albumin ratio

Author contributions

K Toprak contributed to acquisition, analysis and interpretation of data; revising it critically for important intellectual content; and final approval of the version to be published. K Özen contributed to acquisition, analysis and interpretation of data; drafting the article; revising it critically for important intellectual content; and final approval of the version to be published. T Memioğlu and M İnanır contributed to the acquisition, analysis and interpretation of data; drafting the article; and final approval of the version to be published. S Akyol, M Begenc Tascanov and A Biçer made substantial contributions to conception and design; drafting the article; and final approval of the version to be published. M Kaplangöray contributed to acquisition of data; drafting the article; and final approval of the version to be published. R Demirbağ made substantial contributions to conception and design; revising the article critically for important intellectual content; and final approval of the version to be published.

Financial disclosure

The authors have no financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Competing interests disclosure

The authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Writing disclosure

No writing assistance was utilized in the production of this manuscript.

Ethical conduct of research

The authors state that they have obtained appropriate institutional review board approval or have followed the principles outlined in the Declaration of Helsinki for all human or animal experimental investigations. In addition, for investigations involving human subjects, informed consent has been obtained from the participants involved.