The Ups and Downs of DNA Methylation: An Interview with Gerd Pfeifer

Abstract

In this interview, Professor Gerd Pfeifer speaks with Storm Johnson, Commissioning Editor for Epigenomics, on his work to date in the field of DNA methylation.

Dr Pfeifer received a PhD degree from the University of Frankfurt, Germany. After postdoctoral work, he became a faculty member at the Beckman Research Institute of the City of Hope (Duarte, CA) in 1991. He is currently a full professor at the Van Andel Institute in Grand Rapids, MI. Dr. Pfeifer has served on several NIH advisory committees and has published over 300 research papers. Dr Pfeifer’s research interests are cancer etiology, molecular carcinogenesis and epigenetics. His expertise is in cellular and molecular biology. His lab currently works on epigenetic mechanisms of gene regulation in cancer and other diseases.

Keywords::

• 5-methylcytosine
• demethylation
• DNA methylation
• TET proteins

Financial&competing interests disclosure

G Pfeifer is a member of the Epigenomics editorial board. The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Interview disclosure

The opinions expressed in this interview are those of Gerd Pfeifer and do not necessarily reflect the views of Future Medicine Ltd.