Financial & competing interests disclosure
JN Lowder and P Taverna are employees of Astex Pharmaceuticals. J-PJ Issa is an investigator and research collaborator with Astex Pharmaceuticals. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.