Abstract
What is this summary about?
This is a summary of a research study called revised STARS. The STARS study involved people with non-small-cell lung cancer, also known as NSCLC. The cancer was less than 5 cm in size and had not spread to other parts of the body (known as stage 1 cancer). The study compared the effectiveness of surgery versus a type of radiotherapy treatment, called stereotactic ablative radiotherapy (also known as SABR) as a treatment for people with NSCLC. Researchers wanted to find out how likely people were to be alive after treatment or if their cancer had grown or spread to other parts of their body (also known as progressed).
What were the results?
The study found that the long term outcomes were similar between SABR and surgery. People with NSCLC were as likely to be alive 3 years after treatment with SABR compared to surgery.
What do the results of the study mean?
SABR may be an alternative to surgery for people with stage 1 NSCLC which is less than 5 cm in size and has not spread to other parts of the body
Clinical Trial Registration: NCT02357992 (ClinicalTrials.gov)
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Link to original article here
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045
Acknowledgments
This article was selected by a Steering Committee, put together by the Future Science Group, who identified specific articles to be explained as a plain language summary to help educate about the latest developments in non-small cell lung cancer. The authors would like to thank the Steering Committee for their role in this selection process. Medical writing assistance was provided by Catherine Barras, MSc and Danielle Birchall, MRes MICR, of Simplifying Science® and was supported financially by Future Science Group, through an Independent Medical Education Grant provided by Pfizer, Inc. Simplifying Science® is a registered trademark in Great Britain and Northern Ireland. Trademark No. UK00003709258. Owned by and registered to Lay Writing Services Ltd.
Financial & competing interests disclosure
The Steering Committee were compensated for their time in the process of article selection as described above. The authors did not receive payment related to the development of the plain language summary of publication.