Consensus Statement from the International Radiosurgery Oncology Consortium for Kidney for Primary Renal Cell Carcinoma

ABSTRACT

Aim: To provide a multi-institutional consensus document for stereotactic body radiotherapy of primary renal cell carcinoma. Materials & methods: Eight international institutions completed a 65-item survey covering patient selection, planning/treatment aspects and response evaluation. Results: All centers treat patients with pre-existing hypertension and solitary kidneys. Five institutions apply size constraints of 5–8 cm. The total planning target volume expansion is 3–10 mm. All institutions perform pretreatment imaging verification, while seven institutions perform some form of intrafractional monitoring. Number of fractions used are 1–12 to a total dose of 25 Gy–80 GyE. Imaging follow-up for local tumor response includes computed tomography (n = 8), PET-computed tomography (n = 1) and MRI (n = 5). Follow-up frequency is 3–6 months for the first 2 years and 3–12 months for subsequent 3 years. Conclusion: Key methods for safe implementation and practice for stereotactic body radiotherapy kidney have been identified and may aid standardization of treatment delivery.

KEYWORDS:

• ablation
• kidney cancer
• patterns of practice
• radiotherapy
• SABR
• SBRT
• stereotactic

Financial & competing interests disclosure

S Siva, BS Teh, T Nomiya, P Wersall, M Staehler, A Muacevic, H Onishi do not have conflicts of interest relevant to the present work. SS Lo has received travel expenses and honorarium from Varian Medical Systems and research support from Elekta, and received travel support and honorarium from Accuray to speak in a users’ meeting. RJ Ellis has received research funding from Elekta AB and Philips. A Muacevic has received speakers honoraria from Accuray. L Ponsky has received research grants from Accuray. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Supplementary data

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