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Abstract
Nanotechnology manipulates therapeutic agents at the nanoscale for the development of nanomedicines. However, there are current concerns over nanomedicines, mainly related to the possible toxicity of nanomaterials used for health medications. Due to their small size, they can enter the human body more readily than larger sized particles. Green chemistry encompasses the green synthesis of drug-loaded nanoparticles by reducing the use of hazardous materials in the synthesis process, thus reducing the adverse health impacts of pharmaceutics. This would greatly expand their potential in biomedical treatments. This review highlights the potential risks of nanomedicine formulations to health, delivery routes of green nanomedicines, recent advances in the development of green nanoscale systems for biomedical applications and future perspectives for the green development of nanomedicines.
Financial & competing interests disclosure
This work is supported by the Innovation Technology Commission to ABCT, HKPU, and the account codes: FRG1/14–15/021 and 3840116 (CH Chui) as well as 03–16–176 (XZ Bian). R Gambari is supported by AIRC (IG-13575). W-Y Wong is supported by (RC-ICRS/15–16/02) from HKBU. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
Language editing for this manuscript was provided by the Enago, Crimson Interactive Inc., supported by 3840116 (CH Chui).