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Disclaimer
The views expressed in this editorial are those of the authors and do not necessarily reflect the views or opinions of the Medicines and Healthcare products Regulatory Agency, other regulatory authorities or any of their advisory bodies.
Financial & competing interests disclosure
R Shah was formerly a Senior Clinical Assessor at the Medicines and Healthcare products Regulatory Agency, London, UK, and now provides expert consultancy services on cardiac safety of new drugs to a number of pharmaceutical companies. R Smith is Emeritus Professor of Pharmacology at the Imperial College London and Senior Research Fellow in the Department of Surgery and Cancer. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.