Abstract
Background: Sacroiliac joint (SIJ) pain is a common source of lower back pain; the factors associated have not been studied in cancer patients. Observing patients with bone marrow aspiration and biopsy (BMAB) who subsequently developed SIJ-pain led to this investigation. Aim: To investigate this possible relationship. Methods: A cohort study of cancer patients diagnosed with SIJ pain. The association of BMAB with SIJ pain was evaluated, as were variables that differed between the groups. Results: The prevalence of SIJ pain was 4.95% (231/4669). Among 231 patients with SIJ pain, 34% (78/231) did not have prior history of lower back pain and had undergone BMAB prior to their diagnosis of SIJ pain. A statistically significant association between BMAB–SIJ-pain was found (p < 0.01). Conclusion: We found linear correlation between BMAB and subsequent SIJ pain.
Author contributions
Authors had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis. C Roldan designed the protocol of the study. C Roldan, B Huh, T Chai and L Driver reviewed the charts and collected the data, also participated on the manuscript writing. S Thakur participated on manuscript writing. J Song participated as biostatistician and processed the data collected. C Roldan provided revision for intellectual content and final approval of the manuscript.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.
Ethical consent disclosure
Direct patient participation was not necessary, and informed consent was not obtained due to the retrospective nature of the study.