Fatty acid composition of palatal tissue from denture stomatitis patients

Henning Lygre Department of Dental Biomaterials and Department of Oral Medicine and Oral Surgery, School of Dentistry, and Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway; Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway

Einar Solheim Department of Dental Biomaterials and Department of Oral Medicine and Oral Surgery, School of Dentistry, and Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway; Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway

Nils Roar Gjerdet Department of Dental Biomaterials and Department of Oral Medicine and Oral Surgery, School of Dentistry, and Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway; Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway

Mons Espelid Department of Dental Biomaterials and Department of Oral Medicine and Oral Surgery, School of Dentistry, and Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway; Department of Clinical Biology, Section of Oral Pharmacology, School of Medicine, University of Bergen, Bergen, Norway

Abstract

Palatal biopsy specimens were obtained from patients with denture stomatitis. The fatty acids were extracted from the tissue, then separated, identified, and quantified by a gas-chromatographic technique. The sensitivity of this method enabled analyses of specimens with a wet weight of less than 1 mg. The concentration of the fatty acids C16: 1(n-7) and C24: 1(n-9) differed significantly between samples from hyperplastic and clinically healthy tissue in the denture stomatitis patients. By comparing specimens from denture stomatitis patients and non-denture subjects, the concentration of seven fatty acids, two saturated and five unsaturated, was found to be significantly different. A multivariate data-analytical method distinguished between the fatty acid composition in specimens from denture stomatitis patients and from non-denture subjects.

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Fatty acid composition of palatal tissue from denture stomatitis patients

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Fatty acid composition of palatal tissue from denture stomatitis patients

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