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Original Article

Comparison of Hearing Thresholds and Morphological Changes in the Chinchilla After Exposure to 4 Khz Tones

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Pages 192-206 | Received 18 Jan 1974, Published online: 08 Jul 2009
 

Abstract

Behavioral, anatomical and histochemical effects of acoustic overstimulation produced by a 4 cHz tone were investigated. In each of five monaural chinchillas, high frequency hearing loss was produced which was related to locus and extent of hair cell loss. Masked audiograms were fairly consistent with those obtained in quiet and the anatomical data on presence or absence of hair cells. Histochemical and electron microscope examination of selected portions of the cochlear partition revealed a series of changes in hair cells which may or may not influence their functional properties.

ZUSAMMENFASSUNG

Die Wirkungen akustischer überreizung auf anatomische, histochemische und Verhaltens-Parameter wurden an fünf einohrigen Chinchillas untersucht. Beschallung erfolgte mit einem Dauerton von 4 kHz. Die an Hand von Audiogrammen festgestellten Hörausfälle stimmten ziemlich gut mit der Lokalisation sowie der Ausdehnung des Haarzellen untergangs im Cortischen Organ überein. An Haarzellen ausserhalb der Hauptzerstörungsherde wurden ferner eine Reihe von histochemischen und ultrastrukturellen Veränderungen festgestellt, deren funktionelle Bedeutung noch unklar ist.

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