Damaged utricular function clarified by oVEMP in patients with benign paroxysmal positional vertigo

Abstract

Conclusion: Utricular dysfunction in patients with posterior canal benign paroxysmal positional vertigo (pBPPV) was supported by findings for ocular vestibular evoked myogenic potential (oVEMP). Objective: To evaluate the utricular and saccular function in patients with pBPPV. Methods: This study focused on 12 patients definitively diagnosed with pBPPV showing typical nystagmus by Dix-Hallpike maneuver and 12 controls. In these subjects, oVEMPs and cVEMPs to air-conducted 500 Hz tone burst (125 dB SPL) were measured. The patients also underwent caloric tests. Results: More of the patients with pBPPV showed abnormal responses in oVEMPs by stimulation on their affected side than the controls, while the results of cVEMPs showed no significant differences between pBPPV patients and controls. The abnormal results for oVEMPs on the affected side showed a higher percentage than those for cVEMPs and caloric tests in pBPPV patients. There was no significant association between any of the tests. These findings support the possibility that oVEMP reflects the specific abnormal condition in pBPPV, i.e. that the urticular function in pBPPV patients was highly damaged.

Keywords::

• Ocular vestibular evoked myogenic potential
• otolith
• utricle
• VEMP

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.