Analysis of factors in successful nasal endoscopic resection of nasopharyngeal angiofibroma

Abstract

Conclusions: Endoscopic resection of nasopharyngeal angiofibroma is less traumatic, causes less bleeding, and provides a good curative effect. Using pre-operative embolization and controlled hypotension, reasonable surgical strategies and techniques lead to successful resection tumors of a maximum Andrews-Fisch classification stage of III. Objective: To investigate surgical indications, methods, surgical technique, and curative effects of transnasal endoscopic resection of nasopharyngeal angiofibroma, this study evaluated factors that improve diagnosis and treatment, prevent large intra-operative blood loss and residual tumor, and increase the cure rate. Methods: A retrospective analysis was performed of the clinical data and treatment programs of 23 patients with nasopharyngeal angiofibroma who underwent endoscopic resection with pre-operative embolization and controlled hypotension. The surgical method applied was based on the size of tumor and extent of invasion. Curative effects were observed. Results: No intra-operative or perioperative complications were observed in 22 patients. Upon removal of nasal packing material 3–7 days post-operatively, one patient experienced heavy bleeding of the nasopharyngeal wound, which was treated compression hemostasis using post-nasal packing. Twenty-three patients were followed up for 6–60 months. Twenty-two patients experienced cure; one patient experienced recurrence 10 months post-operatively, and repeat nasal endoscopic surgery was performed and resulted in cure.

Keywords:

• Nasal endoscopy
• surgery
• treatment
• prognosis

Acknowledgements

This work was supported by grants from the Scientific Innovation Team Project of Ningbo (No.2012B82019), Ningbo Social Developmental Key Research Project (No.2012C5015), Natural Science Foundation of Ningbo (No.2013A610217), Medical and Health Training Project of Zhejiang Province (No.2015RCB025).

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.