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Abstract
The cerebral perfusion of a 55-year-old female patient with chronic tinnitus was investiga quantitatively by single photon emission computed tomography (SPECT) with the xenoi inhalation method. The first investigation was performed under standard conditions, second during suppression of tinnitus with intravenous injection of lidocaine. As a refere a healthy volunteer was included under the same conditions. The global cortical perfus was identical on both sides except for increased perfusion in the auditory cortex, especi; on the right side when tinnitus lasted during the first measurement. The second investigat under treatment with lidocaine and during the tinnitus-free interval showed a decrease of global cortical perfusion with a slightly higher value at the temporal cortex bilaterally. comparison to the first investigation, a difference between right and left auditory coi could no longer be demonstrated, and also the difference between regional and glo perfusion decreased. A cerebral effect under treatment of tinnitus with lidocaine was she by the quantitative measurement of brain perfusion. It is debatable whether this effect cerebral activity results from the medication or as a reaction to the tinnitus-free interval.