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International Journal of Neuroscience Volume 120, 2010 - Issue 12
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Research Article

Temozolomide for Adult Brain Stem Glioblastoma: Case Report of a Long-Term Survivor

Chao ZhangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
,
Yu YaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
,
Yin WangDepartment of Neuropathology, Huashan Hospital, Fudan University, Shanghai, China
,
Zheng ChenDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
,
Jinsong WuDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
,
Ying MaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, ChinaCorrespondence[email protected]
&
Liangfu ZhouDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
 show all
Pages 787-791 | Received 28 Apr 2010, Published online: 15 Oct 2010
 
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ABSTRACT

Brain stem gliomas are rare intracranial tumors, especially in adults. Malignant or high-grade brain stem gliomas are usually associated with a very poor prognosis. This case report documents an adolescent harboring brain stem glioblastoma who had complete radiological response to temozolomide after partial tumor resection and survived for more than 3 years. Radiological and pathological findings are described. To the best of our knowledge, no similar cases have been reported in the literature.

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