Erp Spectral Analysis of Cholesterol Rich Patients

Abstract

Visual event-related potentials (ERPs) were studied in twenty hypercholesterolemic (HC) patients and twenty age-matched healthy controls. ERPs were recorded in two different experimental conditions that the target stimulus (red light) was counted (Test I) or uncounted (Test 2). Amplitude spectra of ERPs were computed by transient response-frequency characteristics (TRFC) method. Their maxima were found to occupy the frequency bands of 1-2, 3-4, 5-7, 8-12, 13-20, 20.5-32 Hz. The amplitude mean (decibel) of 1-2 and 3-4 frequency bands were decreased in Test 2 compared to Test 1 in the control group, but no significant amplitude differences were found between Test 1 and Test 2 in the HC group.

Key Words:

• event-related potentials
• P₃ (P₃₀₀)
• visual
• spectral analysis
• decision-making
• hypercholesterolemia