Abstract
A procoagulant from postpartum serum has been studied.
It is assayed in a two-stage thrombin generation system with partially purified clotting factors. The procoagulant promotes activation of prothrombin to thrombin under the influence of factors V, VII, and X. Phospholipid increases its activity.
The procoagulant has most of the characteristics of tissue thromboplastin (tissue extract).