Metabolism of γG-globulin in the Nephrotic Syndrome in Adults

S. Bryde Andersen Department of Clinical Physiology and Medical Department F, Glostrup Hospital, Copenhagen; Medical Department P, Rigshospitalet, Copenhagen

S. Jarnum Department of Clinical Physiology and Medical Department F, Glostrup Hospital, Copenhagen; Medical Department P, Rigshospitalet, Copenhagen

H. Jensen Department of Clinical Physiology and Medical Department F, Glostrup Hospital, Copenhagen; Medical Department P, Rigshospitalet, Copenhagen

N. Rossing Department of Clinical Physiology and Medical Department F, Glostrup Hospital, Copenhagen; Medical Department P, Rigshospitalet, Copenhagen

Abstract

Eleven patients out of sixteen with the nephrotic syndrome had a subnormal concentration of γG-globulin in serum. The low concentration was caused partly by urinary loss and partly by an increased catabolic rate of γG-globulin. The rate of synthesis was increased in eleven out of sixteen patients. This may indicate an abnormal function of the immune apparatus in the nephrotic syndrome.

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Metabolism of γG-globulin in the Nephrotic Syndrome in Adults

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Metabolism of γG-globulin in the Nephrotic Syndrome in Adults

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