The Effect of Guar Gum and Fiber-Enriched Wheat Bran on Gastric Emptying of a Semisolid Meal in Healthy Subjects

Abstract

The effect of physiological doses of guar gum (Guarem), 5 g. and fiber-enriched wheat bran (Fiberform), 10.5 g, on gastric emptying was studied by two different methods in healthy subjects: by a simple isotope localization monitor placed over the upper part of the abdomen and by gamma camera. The fiber preparations were added to a semisolid meal consisting of wheatmeal porridge and juice, using technetium-99 DTPA as a marker. The gamma camera showed no effect of fiber on gastric emptying. The isotope localization monitor, however, indicated that Fiberform prevented a postprandial accumulation of the meal within the upper part of the stomach. The simple isotope localization monitor cannot be recommended for measurements of gastric emptying.

Key Words:

• Gamma camera
• gastric emptying
• guar gum
• healthy subjects
• isotope localization monitor
• wheat bran
• fiber-enriched