Detection of carbapenem resistance in clinical mucoid Pseudomonas aeruginosa isolates

Abstract

Of 19 isolates of mucoid Pseudomonas aeruginosa, 2 isolates showed imipenem resistance conferred by reduced OprD production. Imipenem resistance was detected by the MicroScan broth microdilution and Etest methods, but minimum inhibitory concentrations could not be determined by the Vitek system for an isolate. In cases where susceptibility cannot be determined by the broth microdilution methods, Etest results would be valuable for effective treatment.