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Scandinavian Journal of Infectious Diseases Volume 46, 2014 - Issue 3
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CASE REPORTS

Recurrent bone fractures due to tenofovir-induced renal phosphate wasting

Katrin F. KoenigFrom the Division of Nephrology, Kantonsspital Baselland, Liestal
,
Stefan KalbermatterFrom the Division of Nephrology, Kantonsspital Baselland, Liestal
,
Thomas MenterInstitute for Pathology, University Hospital Basel, Basel
,
Peter GraberDivision of Infectious Disease, Kantonsspital Baselland, Liestal, Switzerland
&
Denes KissFrom the Division of Nephrology, Kantonsspital Baselland, LiestalCorrespondence[email protected]
Pages 221-224 | Received 09 Aug 2013, Accepted 18 Aug 2013, Published online: 22 Oct 2013
 
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Abstract

A 42-y-old HIV-infected man suffered from several stress fractures due to tenofovir-induced proximal tubular injury. Laboratory examination revealed hypophosphatemia due to renal phosphate wasting. Therefore, more attention has to be paid to the monitoring of serum phosphate and alkaline phosphatase levels, since tenofovir-related nephrotoxicity increases the risk of osteomalacia.

Declaration of interest: No conflict of interest.

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