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Infectious Diseases Volume 47, 2015 - Issue 2
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Case Report

Dramatic response to itraconazole in central nervous system aspergillosis complicating acute promyelocytic leukemia

Hong-Ling Peng From the Department of Hematology, Second Xiang-ya Hospital, Central South University, Changsha, Hunan, P. R. China
,
Yi-Fang Yi From the Department of Hematology, Second Xiang-ya Hospital, Central South University, Changsha, Hunan, P. R. China
,
Xiao-Hui Shen From the Department of Hematology, Second Xiang-ya Hospital, Central South University, Changsha, Hunan, P. R. China
,
Ya-Fei Yin From the Department of Hematology, Second Xiang-ya Hospital, Central South University, Changsha, Hunan, P. R. China
&
Guang-Sen Zhang From the Department of Hematology, Second Xiang-ya Hospital, Central South University, Changsha, Hunan, P. R. ChinaCorrespondence[email protected]
Pages 104-106 | Received 19 Aug 2014, Accepted 10 Sep 2014, Published online: 26 Nov 2014
 
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Abstract

Fungal infection is a rare complication of acute leukemia, in which a combination of voriconazole and amphotericin B is a first-line regimen of treatment. Here administration of itraconazole plus caspofungin resulted in a dramatic response in a patient with acute promyelocytic leukemia (APL).

Declaration of interest: The authors report no conflicts of interest.

This work was supported by National Nature Science Fund (81200368) and The International Cooperation Project of Hunan Provincial Department of Science and Technology (No. 2011wk3043).

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